靶标:
ARHGEF4
产品别名:
ASEF; ASEF1; GEF4; SMIM39; STM6; ARHGEF4; Rho guanine nucleotide exchange factor 4; Rho guanine nucleotide exchange factor 4; rho guanine nucleotide exchange factor 4; APC-stimulated guanine nucleotide exchange factor 1; Rho guanine nucleotide exchange factor (GEF) 4;
背景信息:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013],