靶标：
PDE11A
产品别名：
PPNAD2； PDE11A； phosphodiesterase 11A； phosphodiesterase 11A； dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A； cAMP and cGMP cyclic nucleotide phosphodiesterase 11A； 磷酸二酯酶11A；
背景信息：
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
