靶标：
TPRKB
产品别名：
CGI-121； CGI121； GAMOS5； TPRKB； TP53RK binding protein； TP53RK binding protein； EKC/KEOPS complex subunit TPRKB； PRPK (p53-related protein kinase)-binding protein； p53相关蛋白激酶结合蛋白；
背景信息：
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.
