靶标：
ASCC1
产品别名：
ASC1p50； CGI-18； SMABF2； p50； ASCC1； activating signal cointegrator 1 complex subunit 1； activating signal cointegrator 1 complex subunit 1； activating signal cointegrator 1 complex subunit 1； ASC-1 complex subunit P50； trip4 complex subunit p50；
背景信息：
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
