靶标：
TMX2
产品别名：
CGI-31； NEDMCMS； PDIA12； PIG26； TXNDC14； TMX2； thioredoxin related transmembrane protein 2； thioredoxin related transmembrane protein 2； thioredoxin-related transmembrane protein 2； cell proliferation-inducing gene 26 protein； growth-inhibiting gene 11； protein disulfide isomerase family A, member 12； thioredoxin domain-containing protein 14； 硫氧还蛋白相关跨膜蛋白2；
背景信息：
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines.
