靶标:
NDUFA13
产品别名:
B16.6; CDA016; CGI-39; GRIM-19; GRIM19; MC1DN28; NDUFA13; NADH:ubiquinone oxidoreductase subunit A13; NADH:ubiquinone oxidoreductase subunit A13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; CI-B16.6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13; NADH-ubiquinone oxidoreductase B16.6 subunit; cell death regulatory protein GRIM-19; cell death-regulatory protein GRIM19; complex I B16.6 subunit; complex I-B16.6; gene associated with retinoic and IFN-induced mortality 19 protein; gene associated with retinoic and interferon-induced mortality 19 protein; 干扰素/维甲酸诱导凋亡相关基因;
背景信息:
This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined. [provided by RefSeq, Oct 2009],