靶标：
ANGPTL4
产品别名：
ARP4； FIAF； HARP； HFARP； NL2； PGAR； TGQTL； UNQ171； pp1158； ANGPTL4； angiopoietin like 4； angiopoietin like 4； angiopoietin-related protein 4； PPARG angiopoietin related protein； fasting-induced adipose factor； hepatic angiopoietin-related protein； hepatic fibrinogen/angiopoietin-related protein； peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein； 肝血管生成素相关蛋白4； 血管生成素样蛋白4； 血管生成素样蛋白4(ANGPTL4)；
背景信息：
This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013],
