膜相关环指蛋白2抗体

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膜相关环指蛋白2抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Anti-MARCHF2
Anti-membrane associated ring-CH-type finger 2 Antibody

靶标：

MARCHF2

产品别名：

HSPC240； MARCH-II； MARCH2； RNF172； MARCHF2； membrane associated ring-CH-type finger 2； membrane associated ring-CH-type finger 2； E3 ubiquitin-protein ligase MARCHF2； E3 ubiquitin-protein ligase MARCH2； RING finger protein 172； RING-type E3 ubiquitin transferase MARCH2； RING-type E3 ubiquitin transferase MARCHF2； membrane associated ring finger 2； membrane-associated RING finger protein 2； membrane-associated RING-CH protein II； membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase；膜相关环指蛋白2；

背景信息：

MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010],