靶标：
TAOK3
产品别名：
DPK； JIK； MAP3K18； hKFC-A； TAOK3； TAO kinase 3； TAO kinase 3； serine/threonine-protein kinase TAO3； CTCL-associated antigen HD-CL-09； JNK/SAPK-inhibitory kinase； STE20-like kinase； cutaneous T-cell lymphoma-associated antigen HD-CL-09； dendritic cell-derived protein kinase； jun kinase-inhibitory kinase； kinase from chicken homolog A； thousand and one amino acid protein 3； JNK/ SAPK抑制激酶；
背景信息：
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Also localized to the peripheral cell membrane.,subunit:Self-associates.,tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.,
