靶标：
ATP6V1D
产品别名：
ATP6M； VATD； VMA8； ATP6V1D； ATPase H+ transporting V1 subunit D； ATPase H+ transporting V1 subunit D； V-type proton ATPase subunit D； ATPase, H+ transporting lysosomal, member M； ATPase, H+ transporting, lysosomal (vacuolar proton pump)； ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D； H(+)-transporting two-sector ATPase, subunit M； V-ATPase 28 kDa accessory protein； V-ATPase D subunit； V-ATPase subunit D； vacuolar ATP synthase subunit D； vacuolar H-ATPase subunit D； vacuolar proton pump D subunit； vacuolar proton pump delta polypeptide； vacuolar proton pump subunit D； vacuolar proton-ATPase subunit D；
背景信息：
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008],
