靶标:
WNT16
产品别名:
WNT16; Wnt family member 16; Wnt family member 16; protein Wnt-16; wingless-type MMTV integration site family member 16b; wingless-type MMTV integration site family, member 16; 信号通路Wnt16; 无翅型MMTV整合位点家族成员16(WNT16);
背景信息:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. [provided by RefSeq, Jul 2008],