靶标:
DCDC2
产品别名:
DCDC2A; DFNB66; NPHP19; NSC; RU2; RU2S; DCDC2; doublecortin domain containing 2; doublecortin domain containing 2; doublecortin domain-containing protein 2; nephronophthisis 19; 双皮层蛋白结构域蛋白DCDC2;
背景信息:
This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2013]