靶标：
ATP6V1H
产品别名：
CGI-11； MSTP042； NBP1； SFD； SFDalpha； SFDbeta； VMA13； ATP6V1H； ATPase H+ transporting V1 subunit H； ATPase H+ transporting V1 subunit H； V-type proton ATPase subunit H； ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H； V-ATPase 50/57 kDa subunits； V-ATPase subunit H； nef-binding protein 1； protein VMA13 homolog； vacuolar ATP synthase subunit H； vacuolar ATPase subunit H； vacuolar proton pump subunit H； vacuolar proton pump subunit SFD；
背景信息：
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
