靶标：
CHMP3
产品别名：
CGI-149； NEDF； VPS24； CHMP3； charged multivesicular body protein 3； charged multivesicular body protein 3； charged multivesicular body protein 3； 25.1 protein； CHMP family, member 3； chromatin-modifying protein 3； neuroendocrine differentiation factor； vacuolar protein sorting 24 homolog； vacuolar protein sorting-associated protein 24； 液泡蛋白分选蛋白24；
背景信息：
This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]
