靶标:
PALS2
产品别名:
MPP6; VAM-1; VAM1; p55T; PALS2; protein associated with LIN7 2, MAGUK p55 family member; protein associated with LIN7 2, MAGUK p55 family member; protein PALS2; MAGUK p55 subfamily member 6; MAGUK protein p55T; VELI-associated MAGUK 1; membrane palmitoylated protein 6; membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6); protein associated with LIN7 2, MAGUK family member; protein associated with Lin7 2; 棕榈酰化膜蛋白6; 棕榈酰化膜蛋白6(MPP6);
背景信息:
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008],