靶标:
PTOV1
产品别名:
ACID2; PTOV-1; PTOV1; PTOV1 extended AT-hook containing adaptor protein; PTOV1 extended AT-hook containing adaptor protein; prostate tumor-overexpressed gene 1 protein; activator interaction domain-containing protein 2; prostate tumor overexpressed 1; 前列腺肿瘤高表达蛋白1;
背景信息:
Prostate tumor overexpressed gene 1 protein is a protein that in humans is encoded by the PTOV1 gene. It is mapped to 19q13.33. This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants.