靶标：
S1PR5
产品别名：
EDG8； Edg-8； S1P5； SPPR-1； SPPR-2； S1PR5； sphingosine-1-phosphate receptor 5； sphingosine-1-phosphate receptor 5； sphingosine 1-phosphate receptor 5； S1P receptor 5； S1P receptor Edg-8； endothelial differentiation G-protein-coupled receptor 8； endothelial differentiation, sphingolipid G-protein-coupled receptor, 8； sphingosine 1-phosphate receptor EDG8； sphingosine 1-phosphate receptor Edg-8； 内皮细胞分化G蛋白偶联受体8；
背景信息：
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008],
