鳞状细胞癌相关蛋白抗体

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鳞状细胞癌相关蛋白抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Anti-DCUN1D1
Anti-defective in cullin neddylation 1 domain containing 1 Antibody

靶标：

DCUN1D1

产品别名：

DCNL1； DCUN1L1； RP42； SCCRO； SCRO； Tes3； DCUN1D1； defective in cullin neddylation 1 domain containing 1； defective in cullin neddylation 1 domain containing 1； DCN1-like protein 1； DCN1, defective in cullin neddylation 1, domain containing 1； DCUN1 domain-containing protein 1； RP42 homolog； defective in cullin neddylation protein 1-like protein 1； squamous cell carcinoma-related oncogene；鳞状细胞癌相关蛋白；

背景信息：

Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8 thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。