靶标:
FBXO42
产品别名:
Fbx42; JFK; FBXO42; F-box protein 42; F-box protein 42; F-box only protein 42; just one F-box and Kelch domain-containing protein; FBXO42蛋白;
背景信息:
Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Dec 2010]