靶标:
ROBO4
产品别名:
AOVD3; ECSM4; MRB; ROBO4; roundabout guidance receptor 4; roundabout guidance receptor 4; roundabout homolog 4; roundabout homolog 4, magic roundabout; roundabout, axon guidance receptor, homolog 4; 肿瘤血管内皮调节蛋白Robo4;
背景信息:
function:Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins.,similarity:Belongs to the immunoglobulin superfamily. ROBO family.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with SLIT2 and ENAH.,tissue specificity:Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.,