靶标:
DNAJB12
产品别名:
DJ10; DNAJB12; DnaJ heat shock protein family (Hsp40) member B12; DnaJ heat shock protein family (Hsp40) member B12; dnaJ homolog subfamily B member 12; DnaJ (Hsp40) homolog, subfamily B, member 12; DNAJB12蛋白;
背景信息:
DNAJB12 belongs to the evolutionarily conserved DNAJ HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine phenylalanine (G F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]