靶标:
PIGX
产品别名:
PIG-X; PIGX; phosphatidylinositol glycan anchor biosynthesis class X; phosphatidylinositol glycan anchor biosynthesis class X; phosphatidylinositol-glycan biosynthesis class X protein; GPI-mannosyltransferase subunit;
背景信息:
This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],