靶标:
NEIL3
产品别名:
FGP2; FPG2; NEI3; ZGRF3; hFPG2; hNEI3; NEIL3; nei like DNA glycosylase 3; nei like DNA glycosylase 3; endonuclease 8-like 3; DNA glycosylase FPG2; DNA glycosylase hFPG2; DNA glycosylase/AP lyase Neil3; endonuclease VIII-like 3; nei endonuclease VIII-like 3; nei-like protein 3; zinc finger, GRF-type containing 3; Nei内切核酸酶Ⅷ样蛋白3(NEIL3);
背景信息:
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008],