靶标：
RBM38
产品别名：
HSRNASEB； RNPC1； SEB4B； SEB4D； dJ800J21.2； RBM38； RNA binding motif protein 38； RNA binding motif protein 38； RNA-binding protein 38； CLL-associated antigen KW-5； RNA-binding region (RNP1, RRM) containing 1； RNA-binding region-containing protein 1； ssDNA-binding protein SEB4； RNA结合基元蛋白38(RBM38)； RNA结合蛋白38；
背景信息：
RBM38 (RNA-binding protein 38), also known as RNPC1 or SEB4. RBM38 is a cell cycle protein found in the cytosol and the Nucleus that exists as two alternatively spliced isoforms, 1 (RNPC1a) and 2 (RNPC1b), of 239 and 121 amino acids, respectively. Independent of p53 expression, RBM38 isoform 1 induces cell cycle arrest in G1 phase through maintaining transcript stability at the 3!?-UTR of p21, a regulator of cell cycle progression at S phase. RBM38 is also an mRNA splicing factor that regulates the expression of FGFR2. RBM38 contains one RRM (RNA recognition motif) domain.
