靶标:
IARS2
产品别名:
CAGSSS; ILERS; IARS2; isoleucyl-tRNA synthetase 2, mitochondrial; isoleucyl-tRNA synthetase 2, mitochondrial; isoleucine--tRNA ligase, mitochondrial; isoleucine tRNA ligase 2, mitochondrial; isoleucine-tRNA synthetase 2, mitochondrial; isoleucyl-tRNA synthetase, mitochondrial; mitochondrial isoleucine tRNA synthetase; tRNA异亮氨酸连接酶;
背景信息:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. This gene encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq, Dec 2014],