靶标：
CHFR
产品别名：
RNF116； RNF196； CHFR； checkpoint with forkhead and ring finger domains； checkpoint with forkhead and ring finger domains； E3 ubiquitin-protein ligase CHFR； RING finger protein 196； RING-type E3 ubiquitin transferase CHFR； checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase； 泛素连接酶蛋白CHFR；
背景信息：
This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014],
