靶标：
VPS11
产品别名：
END1； HLD12； HLD12; DYT32； PEP5； RNF108； hVPS11； VPS11； VPS11 core subunit of CORVET and HOPS complexes； VPS11 core subunit of CORVET and HOPS complexes； vacuolar protein sorting-associated protein 11 homolog； RING finger protein 108； VPS11, CORVET/HOPS core subunit； vacuolar protein sorting 11 homolog； 液泡蛋白分选蛋白11；
背景信息：
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],
