靶标:
KCNQ5
产品别名:
Kv7.5; MRD46; KCNQ5; potassium voltage-gated channel subfamily Q member 5; potassium voltage-gated channel subfamily Q member 5; potassium voltage-gated channel subfamily KQT member 5; KQT-like 5; potassium channel protein; potassium channel subunit alpha KvLQT5; potassium channel, voltage gated KQT-like subfamily Q, member 5; voltage-gated potassium channel subunit Kv7.5; 电压门控钾通道亚基Kv7.5;
背景信息:
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],