靶标:
EIF5A2
产品别名:
EIF-5A2; eIF5AII; EIF5A2; eukaryotic translation initiation factor 5A2; eukaryotic translation initiation factor 5A2; eukaryotic translation initiation factor 5A-2; eIF-5A-2; eukaryotic initiation factor 5A; eIF5A2蛋白;
背景信息:
function:The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.,PTM:eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).,similarity:Belongs to the eIF-5A family.,tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells.,