靶标:
MEPE
产品别名:
OF45; MEPE; matrix extracellular phosphoglycoprotein; matrix extracellular phosphoglycoprotein; matrix extracellular phosphoglycoprotein; matrix, extracellular phosphoglycoprotein with ASARM motif (bone); osteoblast/osteocyte factor 45; osteoregulin; 细胞外基质; 细胞外基质磷酸糖蛋白(MEPE);
背景信息:
This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],