靶标:
NMRAL1
产品别名:
HSCARG; SDR48A1; NMRAL1; NmrA like redox sensor 1; NmrA like redox sensor 1; nmrA-like family domain-containing protein 1; NmrA-like family domain containing 1; epididymis secretory sperm binding protein; short chain dehydrogenase/reductase family 48A, member 1; NMRAL1蛋白;
背景信息:
This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015],