靶标:
CTDSP1
产品别名:
NIF3; NLI-IF; NLIIF; SCP1; CTDSP1; CTD small phosphatase 1; CTD small phosphatase 1; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1; NLI-interacting factor 3; nuclear LIM interactor-interacting factor 3; small C-terminal domain phosphatase 1; 羧基端小结构域磷酸酶1;
背景信息:
CTD small phosphatase 1(CTDSP1) Homo sapiens This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],