凋亡加强结构域蛋白15抗体

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凋亡加强结构域蛋白15抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Anti-NOD2
Anti-nucleotide binding oligomerization domain containing 2 Antibody

靶标：

NOD2

产品别名：

ACUG； BLAU； BLAUS； CARD15； CD； CLR16.3； IBD1； NLRC2； NOD2B； PSORAS1； YAOS； NOD2； nucleotide binding oligomerization domain containing 2； nucleotide binding oligomerization domain containing 2； nucleotide-binding oligomerization domain-containing protein 2； NLR family, CARD domain containing 2； NOD-like receptor C2； caspase recruitment domain family, member 15； caspase recruitment domain protein 15； caspase recruitment domain-containing protein 15； inflammatory bowel disease protein 1； nucleotide-binding oligomerization domain 2； nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2；凋亡加强结构域蛋白15；

背景信息：

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.