靶标:
Ilkap
产品别名:
Ilkap; ILK associated serine/threonine phosphatase; ILK associated serine/threonine phosphatase; integrin-linked kinase-associated serine/threonine phosphatase 2C; PP2Cdelta; protein phosphatase 2C; 整合素连接激酶相关丝氨酸/苏氨酸磷酸酶;
背景信息:
The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq, Jul 2008],