靶标:
AGXT2
产品别名:
AGT2; BAIBA; DAIBAT; AGXT2; alanine--glyoxylate aminotransferase 2; alanine--glyoxylate aminotransferase 2; alanine--glyoxylate aminotransferase 2, mitochondrial; (R)-3-amino-2-methylpropionate--pyruvate transaminase; beta-ALAAT II; beta-alanine-pyruvate aminotransferase; 丙氨酸乙醛酸转氨酶2(AGXT2);
背景信息:
The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],