靶标：
BOLL
产品别名：
BOULE； BOLL； boule homolog, RNA binding protein； boule homolog, RNA binding protein； protein boule-like； bol, boule-like； boule-like RNA binding protein； 精子成熟相关蛋白BOULE；
背景信息：
This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
