靶标:
Pla2g12a
产品别名:
2310004B05Rik; GXII; GXII-1; GXII-1-PLA2; Pla2g12; Rossy; mGXII-1; Pla2g12a; phospholipase A2, group XIIA; phospholipase A2, group XIIA; group XIIA secretory phospholipase A2; group XII-1 phospholipase A2; group XIIA secreted phospholipase A2; phosphatidylcholine 2-acylhydrolase 12A; Ⅻ组磷脂酶A2(PLA2G12);
背景信息:
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).