靶标:
Dusp26
产品别名:
2310043K02Rik; Skrp3; Dusp26; dual specificity phosphatase 26 (putative); dual specificity phosphatase 26 (putative); dual specificity protein phosphatase 26; dual-specificity phosphatase SKRP3; 双特异性磷酸酶26; 双特异性蛋白磷酸酶26;
背景信息:
This gene encodes a member of the tyrosine phosphatase family of proteins and exhibits dual specificity by dephosphorylating tyrosine as well as serine and threonine residues. This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context. This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],