靶标:
Klhl13
产品别名:
1200009K10Rik; AI451128; Bklhd2; D130072F20Rik; Klhl13; kelch-like 13; kelch-like 13; kelch-like protein 13; BTB and kelch domain-containing protein 2; kelch样蛋白13;
背景信息:
This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],