靶标：
Ube2f
产品别名：
2510010F15Rik； AI851109； Ube2f； ubiquitin-conjugating enzyme E2F (putative)； ubiquitin-conjugating enzyme E2F (putative)； NEDD8-conjugating enzyme UBE2F； NEDD8 carrier protein UBE2F； NEDD8 protein ligase UBE2F； NEDD8-conjugating enzyme 2； RING-type E3 NEDD8 transferase UBE2F； ubiquitin-conjugating enzyme E2 F； 泛素结合酶E2F；
背景信息：
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
