靶标:
Gpihbp1
产品别名:
1110002J19Rik; GPI-HBP1; Gpihbp1; GPI-anchored HDL-binding protein 1; GPI-anchored HDL-binding protein 1; glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; high density lipoprotein-binding protein 1; 甘油磷酸肌醇锚定高密度脂蛋白结合蛋白1(GPIHBP1); 高密度脂蛋白结合蛋白1;
背景信息:
This gene encodes a capillary endothelial cell protein that facilitates the lipolytic processing of triglyceride-rich lipoproteins. The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family. This protein plays a major role in transporting lipoprotein lipase (LPL) from the subendothelial spaces to the capillary lumen. Mutations in this gene are the cause of hyperlipoproteinemia, type 1D. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],