靶标：
Atp6v1c2
产品别名：
1110038G14Rik； Atp6v1c2； ATPase, H+ transporting, lysosomal V1 subunit C2； ATPase, H+ transporting, lysosomal V1 subunit C2； V-type proton ATPase subunit C 2； ATPase, H+ transporting, V1 subunit C； V-ATPase subunit C 2； vacuolar proton pump subunit C 2；
背景信息：
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008],
