靶标：
Chac1
产品别名：
1810008K03Rik； Chac1； ChaC, cation transport regulator 1； ChaC, cation transport regulator 1； glutathione-specific gamma-glutamylcyclotransferase 1； ChaC, cation transport regulator-like 1； blocks Notch protein； botch； cation transport regulator-like protein 1； gamma-GCG 1； 阳离子转运调控样蛋白1；
背景信息：
This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016],
