靶标:
Vps26b
产品别名:
1810012I05Rik; 2310075A12Rik; AI848392; Vps26b; VPS26 retromer complex component B; VPS26 retromer complex component B; vacuolar protein sorting-associated protein 26B; vacuolar protein sorting 26 homolog B; vesicle protein sorting 26B;
背景信息:
function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,