靶标：
Arap1
产品别名：
2410002L19Rik； Centd2； mKIAA0782； Arap1； ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1； ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1； arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1； centaurin, delta 2； cnt-d2；
背景信息：
The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],
