靶标：
Ttl
产品别名：
2410003M22Rik； 2700049H19Rik； AI848570； Ttl； tubulin tyrosine ligase； tubulin tyrosine ligase； tubulin--tyrosine ligase；
背景信息：
TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM, Mar 2008],
