靶标:
Cmtm8
产品别名:
2700018N07Rik; AA408515; Cklfsf8; Cmtm8; CKLF-like MARVEL transmembrane domain containing 8; CKLF-like MARVEL transmembrane domain containing 8; CKLF-like MARVEL transmembrane domain-containing protein 8; chemokine-like factor super family 8; chemokine-like factor superfamily member 8; 趋化素样因子超家族成员8; 趋化素样因子超家族成员8(CKLFSF8);
背景信息:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],