靶标:
Trim69
产品别名:
4921519C19Rik; Rnf36; Trif; Trimless; Trim69; tripartite motif-containing 69; tripartite motif-containing 69; E3 ubiquitin-protein ligase TRIM69; RFP-like (B30.2) domain protein; RING finger B-box coiled-coil transcription factor; RING-type E3 ubiquitin transferase TRIM69; ring finger protein 36; testis-specific RING finger protein; tripartite motif-containing protein 69; 环指蛋白36;
背景信息:
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],