靶标:
Pcgf6
产品别名:
4933407A11Rik; AI604840; MBLR; Rnf134; Pcgf6; polycomb group ring finger 6; polycomb group ring finger 6; polycomb group RING finger protein 6; Mel18- and Bmi1-like RING finger protein; ring finger protein 134;
背景信息:
The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.