靶标:
Cenpu
产品别名:
1700029A22Rik; Mlf1ip; Cenpu; centromere protein U; centromere protein U; centromere protein U; CENP-U; MLF1-interacting protein; myeloid leukemia factor 1 interacting protein; 卡波西氏肉瘤疱疹病毒潜伏核抗原相互作用蛋白1; 髓细胞性白血病蛋白1;
背景信息:
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008],